High Performance Carbon Isotope Analysis of LC separated compounds

Elementar’s LiquiFace is the ideal solution for academia based applications requiring high-performance carbon isotope analysis of liquids and separated compounds. LiquiFace offers significant benefits for versatility and ease of use.

Compound-specific isotope analysis of aqueous samples by liquid chromatography is highly advantageous for compound classes that are thermolabile, or require derivatisation prior to gas chromatography analysis. Samples such as carbohydrates, amino acids, alcohols, organic acids and peptides make ideal candidates for LC-IRMS, and the technique has been employed to great success in food and biogeochemistry applications.

LiquiFace is an interface for the LC system to provide quantitative online conversion of organic carbon to CO2, prior to analysis by the IRMS system. The instrument uses a “wet chemical oxidation” which delivers excellent isotopic precision, accuracy and linearity. This level of performance means that LiquiFace covers a range of sample types with a complete independence upon sample concentration, making the analyst’s life even simpler.

  • 100% quantitative conversion of organic carbon to CO2 with sodium persulfate oxidation
  • Robust and thermally stable micro-reactor
  • High efficiency water separation membrane for extraction of dissolved CO2 into He carrier gas with no isotopic fractionation
  • On-board peristaltic pumps provide easily maintained flows of reaction reagents
  • Connection to any standard LC or IC pumping system using finger-tight peek union connections
  • In-line direct injection valve and 25 μl sample loop for performing “bulk” δ13C isotope analysis of aqueous samples
  • Exceptional tolerance to high oxygen loads