HPLC or Direct Injection Mode
The LiquiFace can be connected to a HPLC unit to receive a sample liquid stream for conversion to CO2. Alternatively the internal pump on the LiquiFace can be user to carry out direct injection of samples. Peristaltic pumps in the LiquiFace are used to deliver reagents to the reaction site and not the HPLC pump, maximising the user's operational flexibility and choices. Direct injection to the LiquiFace means that users can perform both bulk isotopic analysis and compound-specific analysis using the same system.
No Sample Derivatisation
LC-IRMS of non-polar compounds do not need to undergo complex derivitisations as with the same sample run via GC-IRMS. The removal of any need for derivitisation on these compounds means that back calculations do not need to be performed on the eventual 13C results. In many cases samples need only be diluted with pure water, filtered and than analysed with the LiquiFace.
Exceptional Tolerance to Excess Oxygen
When the LiquiFace is coupled to an IRMS system from Elementar, the result is an exceptional system with an unparalleled tolerance for excess oxygen load. With the use of sodium persulfate as oxidation agent, a large oxygen excess can enter the IRMS and damage the ionisation filament. The unique thorium coating of the isoprime precisION ionisation filament results in life times of years rather than months. This resistance to oxygen means that an on-line reduction furnace to remove excess oxygen is not required, reducing consumables and possible peak broadening.
Reliable Peak Chromatography
The LiquiFace has been completely designed with chromatography in mind. Once your sample is separated by the LC column, then there is minimal detrimental effect of the interface on the chromatography. Therefore, for particularly complex separations the LiquiFace can be depended upon to provide the very best in chromatography performance.
Low Temperature Sample Conversion
Conversion of the aqueous eluent to sample gas is performed in a low temperature reactor at up to 100°C. Low temperature conversion of the eluent allows our interface to analyze thermolabile samples which will disintegrate at elevated temperatures. The mixture of eluent and sample gases, generated in the LiquiFace heater, are cooled to room temperature and then separated in a gas exchanger with the remaining eluent going to a waste line and the sample gas passing through a water removal membrane in to the IRMS.