HPLC or Direct Injection Mode
The LiquiFace can be connected to a HPLC unit to receive a sample liquid stream for conversion to CO2. Alternatively, the internal pump on the LiquiFace can be used to carry out direct injection of samples. Peristaltic pumps in the LiquiFace are used to deliver and mix reagents with the separated compounds in the LC eluent. Direct injection to the LiquiFace means that users can perform both bulk isotopic analysis and compound-specific analysis using the same system.
Reliable peak chromatography
The LiquiFace has been completely designed with chromatography in mind. Once your sample is separated by the LC column, then there is minimal detrimental effect of the interface on the chromatography. Therefore, for particularly complex separations the LiquiFace can be relied up on to maintain the chromatographic integrity of the separated compounds through to the isotope ratio mass spectrometer.
Fractionation-free sample conversion
Conversion of the aqueous eluent to sample gas is performed in a low temperature reactor at up to 100 °C. Low temperature conversion of the eluent allows our interface to analyze thermolabile samples which will disintegrate at elevated temperatures. The mixture of eluent and sample gases, generated in the LiquiFace heater, are cooled to room temperature and then separated in a gas exchanger with the remaining eluent going to a waste line and the sample gas passing through a water removal membrane in to the IRMS.