NPC analysis without compromise
In the past, you had to compromise when determining the net peptide content (NPC) of lyophilized powder. Now the highly sensitive carbon and nitrogen analyzer, UNICUBE® trace, links it all:
Cost-per-analysis of £0.50
Sample prep of 3 min only
Sample size of less than 1 mg
Highest accuracy and precision
Training for your staff
Need to measure additional elements and/or samples?
NPC can be determined just as easily with the “UNICUBE®”, which can measure C, H, N, S, O* and Cl*. In addition to peptides, both instruments can analyze a wide variety of samples such as fluorinated pharmaceutical compounds, chromatography resins, liquid fuels, and inhomogeneous soils.
Delve into real data
The peptidic material is the only source of nitrogen in the lyophilized powder. Therefore, the NPC can be calculated once the absolute amount of nitrogen in the powder has been determined. 20 µg of nitrogen suffice to produce high-quality NPC data via the UNICUBE trace. Explore how the nitrogen results obtained via the UNICUBE trace compare to Bachem's certified values.
Did you know? NPC analysis via the UNICUBE trace fully complies with USP <1057> method 7 procedure 2 and Ph. Eur. monograph 01/2008:02533 method 7B on total protein measurement procedures.
NPC analysis made easy
NPC analysis via the UNICUBE or UNICUBE trace only requires 3 minutes of manual sample preparation and as little as 5 minutes* for the subsequent fully automated analysis. See how this compares to amino acid analysis:
UNICUBE or UNICUBE trace
Amino Acid Analysis
*Depending on analysis mode; nitrogen determination 5 minutes, with simultaneous measurement of CHNS up to 12 minutes
The UNICUBE in action
Discover how analysis runs and maintenance are conducted with ease.
We've got you covered!
To ensure full GMP compliance, we offer:
analyzer qualifications (IQ/OQ/PQ) executed by trained service engineers
21 CFR part 11 software option
reference materials with %CHNOS values traceable to NIST standards
To train staff quickly, we provide:
online and in-person analyzer trainings
instructional videos (e.g. sample preparation, routine maintenance tasks)
support from our application lab personnel
Get in touch with us for more information
You would like to have more information? We will be happy to answer your questions about the UNICUBE®, the UNICUBE trace® and the net peptide determination. Let us know how we can support you.